Sight Sciences showcases results of TearCare technology in dry eye disease trial

Sight Sciences has unveiled information from a trial evaluating its TearCare know-how to Restasis prescription eyedrops in sufferers with dry eye illness.

The Part I outcomes, which had been offered on the American Academy of Optometry’s annual assembly on 11–14 October in New Orleans, exhibit that interventional eyelid procedures with TearCare know-how had been superior to Allergan (AbbVie‘s) Restasis eyedrops, which is the usual remedy for dry eye illness, as measured by the trial’s major endpoint – enchancment of tear break up time.

The TearCare system, which was cleared by the US Food and Drug Administration in December 2021, makes use of localised warmth remedy through non-surgically affixed electrothermal gadgets. The process is used together with guide expression of the meibomian glands by blinking. The machine is used for dry eye illness attributable to meibomian gland dysfunction – some of the widespread causes of the illness.

Sufferers who acquired TearCare remedies had an improved tear break up time of 1.5 seconds from baseline at one week. At six months, the development was 2.5 seconds.

The remedy group and management group had comparable enhancements in affected person reported outcomes measured by Ocular Floor Illness Index scores – the first subjective endpoint.

Saying the presentation in a 13 October press launch, Sight Sciences additionally added that TearCare demonstrated superior ends in assessments of the meibomian glands.

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The potential, randomised, masked, managed trial (NCT04795752) is about to enrol 350 contributors throughout websites within the US. Within the Part II portion of the examine, topics within the Restasis remedy group will cease taking the eyedrops and as a substitute obtain a TearCare-enabled process.

Individuals will then be monitored for an additional six months. Sight Sciences may even measure the sturdiness of the remedy impact by giving sufferers within the TearCare cohort further procedures the place wanted.

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